Description: Salvinorin A propionate is a selective partial agonist at kappa1-opioid receptors (KOR) with a Ki value of 32.6 nM. It inhibits adenylate cyclase (EC50 = 4.7 nM) in HEK293 cells transfected with human KOR. It is selective for KORs over µ, delta, and ORL-1 opioid receptors and has no effect at serotonin,...

Salvinorin A propionate is a selective partial agonist at kappa1-opioid receptors (KOR) with a Ki value of 32.6 nM. It inhibits adenylate cyclase (EC50 = 4.7 nM) in HEK293 cells transfected with human KOR. It is selective for KORs over µ, delta, and ORL-1 opioid receptors and has no effect at serotonin, dopamine,...