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Item number: Cay33143-10

Isoguvacine is a GABAA receptor agonist. It binds to rat synaptic cortical membranes (Ki = 55 nM) and activates alpha1beta2gamma2S, alpha2beta2gamma2S, alpha3beta2gamma2S, alpha5beta2gamma2S, and rho1 subunit-contanining GABAA receptors in a FLIPR assay (EC50s = 13, 4.5, 5.6, 0.78, and 3.1 µM, respectively). It...

Keywords:	1,2,3,6-tetrahydro-4-pyridinecarboxylic acid, monohydrochloride
Application:	GABA(A) receptor agonist
CAS	68547-97-7
MW:	163.6 D

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