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BMS986187
BMS986187

Item number: TGM-T8991-100mg

Description: BMS986187 is a novel Potent and Selective Positive Allosteric Modulators of the delta-Opioid Receptor. Target: Opioid Receptor. Smiles: Cc1ccccc1COc1ccc(cc1)C1C2=C(CC(C)(C)CC2=O)OC2=C1C(=O)CC(C)(C)C2. References: Livingston K E , Stanczyk M A , Burford N , et al. Pharmacological Evidence for a Putative...
Application: Selective positive allosteric delta-opioid Receptor modulator
CAS 684238-37-7
MW: 470.6 D
From 34.00€ *
Review
BMS 986187
BMS 986187

Item number: Cay21549-1

BMS 986187 is a positive allosteric modulator of delta-opioid receptors. In the presence of the endogenous delta-opioid receptor agonist leu-enkephalin, BMS 986187 has an average EC50 value of 30 nM for beta-arrestin recruitment, but has little to no activity in the absence of an agonist. It is 100-fold selective...
Keywords: 3,4,5,6,7,9-hexahydro-3,3,6,6-tetramethyl-9-[4-[(2-methylphenyl)methoxy]phenyl]-1H-xanthene-1,8(2H)-dione
Application: Selective positive allosteric delta-opioid Receptor modulator
CAS 684238-37-7
MW: 470.6 D
From 44.00€ *
Review