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CAY10698
Item number: TGM-T8950-100mg
Description: CAY10698 is a 12-lipoxygenase inhibitor (12-LO, IC50 of 5.1 µM). Target: Lipoxygenase. Smiles: COc1cccc(CNc2ccc(cc2)S(=O)(=O)Nc2nccs2)c1O. References: Chen, X.-S., Kurre, U., Jenkins, N.A., et al. cDNA cloning, expression, mutagenesis of C-terminal isoleucine, genomic structure, and chromosomal...
| Application: | 12-LO inhibitor |
| CAS | 684236-01-9 |
| MW: | 391.46 D |
From 40.00€
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CAY10698
Item number: Cay18582-1
Platelet-type 12-lipoxygenase (12-LO, Cay-10341) catalyzes the formation of 12-HpETE (Cay-44570) from arachidonic acid (Cay-90010). It has been found to be expressed in various tumor cells as well as pancreatic islets and can be activated by inflammatory cytokines. It has also been implicated in the modulation of...
| Keywords: | 4-[[(2-hydroxy-3-methoxyphenyl)methyl]amino]-N-2-thiazolyl-benzenesulfonamide |
| Application: | 12-LO inhibitor |
| CAS | 684236-01-9 |
| MW: | 391.5 D |
From 43.00€
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