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Item number: TGM-T5688-100mg

Description: Micheliolide(MCL) is a sesquiterpene lactone which inhibits various inflammatory response. Target: NF-kappaB, COX, NOS. Smiles: CC1=C2CC[C@@](C)(O)[C@@H]2[C@H]2OC(=O)C(=C)[C@@H]2CC1. References: Sun Z, Li G, Tong T,et al.Micheliolide suppresses LPS-induced neuroinflammatory responses[J].PLoS One. 2017...

Application:	Bioactive sesquiterpene lactone, PKM2 activator
CAS	68370-47-8
MW:	248.32 D

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Micheliolide

Item number: Cay25402-1

Micheliolide is a sesquiterpene lactone and derivative of parthenolide (Cay-70080) that has been found in M. champaca and has diverse biological activities. It is an irreversible activator of the pyruvate kinase M2 isoform (PKM2, EC50 = 6 nM) that decreases viability of HL-60 cells when used at concentrations...

Keywords:	3aS,4,5,7,8,9R,9aS,9bS-octahydro-9-hydroxy-6,9-dimethyl-3-methylene-azuleno[4,5-b]furan-2(3H)-one
Application:	Bioactive sesquiterpene lactone, PKM2 activator
CAS	68370-47-8
MW:	248.3 D

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