3 products were found matching "677338-12-4"!
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PIK-90
Item number: Cay10010749-5
PIK-90 is a potent and cell permeable phosphoinositide 3-kinase (PI3K) inhibitor (IC50 = 11, 350, 18, and 58 nM for p110 subunit isoforms alpha, beta, gamma, and delta, respectively). Through this action, PIK-90 reduces chemotaxis and induces apoptosis in chronic lymphocytic leukemia B cells. It also blocks...
| Keywords: | PIK-85, N-(2,3-dihydro-7,8-dimethoxyimidazo[1,2-c]quinazolin-5-yl)-3-pyridinecarboxamide |
| Application: | PI3K inhibitor |
| CAS | 677338-12-4 |
| MW: | 351.4 D |
From 27.00€
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PIK-90
Item number: SYN-1068-M001
Slightly soluble (<1mg/ml) in DMSO or ethanol. PIK-90 is a potent PI3K inhibitor with IC(50) values of 11, 18, and 58nM for p110alpha, gamma and delta isoforms respectively. It has an IC(50) of 350nM for the p110beta isoform. It also has low mTOR activity. Target: PI3K , Kinase Group: Lipid Kinase , Substrate:...
| Keywords: | PIK90 |
| Application: | PI3K inhibitor |
| CAS | 677338-12-4 |
| MW: | 351,4 D |
From 77.00€
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PIK-90
Item number: TGM-T2461-10mg
Description: PIK-90, a DNA-PK and PI3K inhibitor, suppresses p110alpha( IC50=11 nM), p110gamma(IC50=18 nM) and DNA-PK(IC50=13 nM) . Target: PI3K, DNA-PK. Smiles: COc1ccc2C3=NCCN3C(NC(=O)c3cccnc3)=Nc2c1OC. References: Van Keymeulen A, et al. J Cell Biol. 2006, 174(3), 437-445.
| Application: | PI3K inhibitor |
| CAS | 677338-12-4 |
| MW: | 351.36 D |
From 40.00€
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