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Item number: Cay15324-5

SMER3 is a selective inhibitor of Skp1-Cullin-F-box (SCF)MET30 ubiquitin ligase, an E3 ligase that regulates transcription, cell-cycle control, and immune response. It is a small molecule enhancer of rapamycin (Cay-13346), in that it enhances yeast cell lethality in response to rapamycin. SMER3, at 5 µM, upregulates...

Keywords:	MET30 Antagonist, SCFMET30 Inhibitor, 9H-indeno[1,2-e][1,2,5]oxadiazolo[3,4-b]pyrazin-9-one
Application:	Skp1-Cullin-F-box (SCF)Met30 ubiquitin ligase inhibitor
CAS	67200-34-4
MW:	224.2 D

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