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Linagliptin
Item number: TGM-T0191-100mg
Description: Linagliptin (BI 1356) is a potent, orally bioavailable dihydropurinedione-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. Target: Proteasome, Autophagy, Ferroptosis, DPP-4. Smiles: C(C#CC)N1C2=C(N=C1N3C[C@H](N)CCC3)N(C)C(=O)N(CC4=NC5=C(C(C)=N4)C=CC=C5)C2=O. References:...
| Keywords: | BI 1356 |
| CAS | 668270-12-0 |
| MW: | 472.54 D |
From 40.00€
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Linagliptin
Item number: AG-CR1-3618-M050
White to off-white solid. Soluble in DMSO, ethanol or methanol. Slightly soluble in water (~1mg/ml). Antidiabetic agent, Highly potent and selective competitive inhibitor of dipeptidyl-peptidase 4 (DPP4, DPP IV, CD26), an enzyme that degrades, glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic...
| Keywords: | 8-(3-(R)-Aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydropurine-2,6-dione, BI-1356 |
| Application: | Antidiabetic agent, DPP4 inhibitor |
| CAS | 668270-12-0 |
| MW: | 472,5 D |
From 50.00€
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Linagliptin
Item number: Cay23306-100
Linagliptin is a potent inhibitor of dipeptidyl peptidase 4 (DPP-4) with an IC50 value of 1 nM for human recombinant DPP-4. It is selective, with >10,000-fold selectivity for DPP-4 over a panel of 11 peptidases and proteases. Linagliptin (3 mg/kg) inhibits 90% of plasma DPP-4 activity in rat. It also...
| Keywords: | BI-1356,... |
| Application: | Dipeptidyl peptidase-4 (DPP-4) inhibitor |
| CAS | 668270-12-0 |
| MW: | 472.5 D |
From 86.00€
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Linagliptin
Item number: LKT-L337521.10
Modifies microvascular function
| Application: | Dipeptidyl-peptidase 4 (DPP4) inhibitor |
| CAS | 668270-12-0 |
| MW: | 472.55 D |
From 63.00€
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