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MeBIO
Item number: Cay19573-5
MeBIO is a control analog of the GSK3alpha/beta inhibitor, BIO (Cay-13123). It displays minimal activity against Cdk1/Cyclin B, GSK3alpha/beta, and Cdk5/p25 (IC50s = 92.0, 44-100, and >100 µM, respectively). MeBIO has been identified as an aryl hydrocarbon receptor (AhR) agonist (EC50s = 20 and 93 nM for yeast and a...
| Keywords: | 1-Methyl-6-bromo-indirubin-3'-oxime, Me6BIO,... |
| Application: | BIO control analog, AhR agonist |
| CAS | 667463-95-8 |
| MW: | 370.2 D |
From 44.00€
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Me6BIO
Item number: AG-MR-C0021-M005
Soluble in DMSO or ethanol. Stock solutions can be made up to 10 mM in DMSO. N-methylated inactive control analog of 6-bromoindirubin-3'-oxime (6BIO) (Prod. No. MR-C0019). Displays minimal activity against CDK1/Cyclin B, GSK-3 alpha/beta and CDK5/p25. Aryl hydrocarbon receptor (AhR) agonist, causes redistribution...
| Keywords: | MeBIO, 1-Methyl-6-bromo-indirubin-3'-oxime |
| Application: | AhR agonist, 6BIO control |
| CAS | 667463-95-8 |
| MW: | 370,2 D |
From 116.00€
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MeBIO
Item number: TGM-T21966-100mg
Description: MeBIO is an agonist of aryl hydrocarbon receptor, with IC50 of 44 and 55 µM for GSK-3 and CDK1/CyclinB, respectively. MeBIO does not affect GSK-3beta. Target: Aryl Hydrocarbon Receptor, GSK-3, CDK. Smiles: CN1C(=O)\C(=C2/Nc3ccccc3/C/2=N\O)c2ccc(Br)cc12. References: Meijer L, et al. GSK-3-selective...
| CAS | 667463-95-8 |
| MW: | 370.2 D |
From 34.00€
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