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BIO
BIO

Item number: Cay13123-5

BIO is a cell-permeable bis-indolo (indirubin) compound that acts as a highly potent, selective, reversible, and ATP-competitive inhibitor of GSK3alpha/beta (IC50 = 5 nM). Its specificity has been tested against various cyclin-dependent kinases (CDKs) (IC50s = 83, 300, 320, and 10,000 nM for Cdk5/p25, Cdk2/A,...
Keywords: GSK3 Inhibitor IX, 6-Bromoindirubin-3'-oxime, MLS 2052,...
Application: GSK-3 inhibitor
CAS 667463-62-9
MW: 356.2 D
From 43.00€ *
Review
6BIO
6BIO

Item number: AG-CR1-0056-M001

Phosphoinositide-dependent kinase 1 (PDK1) inhibitor, Potent, reversible and ATP-competitive glycogen synthase kinase-3alpha/beta (GSK-3alpha/beta) inhibitor, JAK/STAT3 signaling inhibitor, Apoptosis inducer, Potent antiproliferative agent in malignant lymphoid cell.
Keywords: 2’Z,3’E)-6-Bromoindirubin-3’-oxime
Application: PDPK1 inhibitor
CAS 667463-62-9
MW: 356,2 D
From 39.00€ *
Review
6BIO
6BIO

Item number: AG-MR-C0019-M010

Soluble in DMSO or ethanol. Stock solutions can be made up to 10 mM in DMSO. Potent, reversible and ATP-competitive glycogen synthase kinase-3alpha/beta (GSK-3alpha/beta) inhibitor. JAK/STAT3 signaling inhibitor. Phosphoinositide-dependent kinase 1 (PDK1) inhibitor. Anticancer compound. Potent antiproliferative...
Keywords: BIO, 6-Bromoindirubin-3'-oxime
Application: GSK-3alpha/beta inhibitor
CAS 667463-62-9
MW: 356,2 D
From 154.00€ *
Review