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Item number: TGM-T3649-100mg

Description: BGP-15 (BGP-15 2HCl) is a PARP inhibitor with protecting effect after ischemia-reperfusion injury. Target: PARP. Smiles: Cl.Cl.N\C(=N/OCC(O)CN1CCCCC1)c1cccnc1. References: Racz I, et al. Biochem Pharmacol. 2002, 63(6):1099-111.

Keywords:	BGP-15 2HCl, BGP15
Application:	PARP inhibitor, insulin sensitizer
CAS	66611-37-8
MW:	351.27 D

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BGP-15

Item number: Cay17503-5

The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis. BGP-15 is a PARP inhibitor and insulin sensitizer. In perfused heart, it blocks self-ADP-ribosylation of nuclear PARP (Ki = 57 µM) and mono-ADP-ribosylation of GRP78, resulting in decreased levels of reactive...

Keywords:	N-[2-hydroxy-3-(1-piperidinyl)propoxy]-3-pyridinecarboximidamide, dihydrochloride
Application:	PARP inhibitor, Insulin sensitizer
CAS	66611-37-8
MW:	351.3 D

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