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Item number: TGM-T3184-100mg

Description: Kevetrin hydrochloride (4-Isothioureidobutyronitrile hydrochloride) is a small molecule and activator of the tumor suppressor protein p53, with potential antineoplastic activity. Target: p53, Mdm2. Smiles: Cl.NC(=N)SCCCC#N. References: Han D., Smalley K. (2015) Targeting the Cell Cycle and p53 in...

Keywords:	4-Isothioureidobutyronitrile hydrochloride, thioureido butyronitrile hydrochloride, Thioureidobutyronitrile HCl
Application:	p53 activator
CAS	66592-89-0
MW:	179.67 D

From 38.00€ *

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Kevetrin (hydrochloride)

Item number: Cay28288-10

Kevetrin is an activator of p53. It increases levels of activated p53 and expression of p21 in A549 cells and decreases expression of the transcription factor E2F1 in a variety of cell lines. Kevetrin decreases cell viability in a panel of cancer cell lines with a mean IC50 value of 0.49 µM. It reduces tumor growth...

Keywords:	4-Isothioureidobutyronitrile, NSC 525990, carbamimidothioic acid, 3-cyanopropyl ester, monohydrochloride
Application:	p53 activator
CAS	66592-89-0
MW:	179.7 D

From 84.00€ *

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