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TGX-221
Item number: TGM-T2661-100mg
Description: TGX-221, an effective, specific, and cell membrane permeable inhibitor of the PI3K p110beta catalytic subunit, is utilized for cancer treatment. Target: PI3K. Smiles: CC(Nc1ccccc1)c1cc(C)cn2c1nc(cc2=O)N1CCOCC1. References: Chaussade C, et al. Biochem J. 2007, 404(3), 449-458.
| Keywords: | TGX221 |
| CAS | 663619-89-4 |
| MW: | 364.44 D |
From 33.00€
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TGX-221
Item number: Cay10007349-1
Phosphatidylinositol 3-kinase (PI3K) catalyzes the phosphorylation of phosphatidylinositol at the 3 position to produce the second messengers phosphatidylinositol-3,4-bisphosphate (PtdIns-(3,4)-P2) and PtdIns-(3,4,5)-P3. Class 1 PI3Ks are composed of a p110 catalytic subunit, of which there are 4 isoforms...
| Keywords: | 7-methyl-2-(4-morpholinyl)-9-[1-(phenylamino)ethyl]-4H-pyrido[1,2-a]pyrimidin-4-one |
| Application: | PI3K p110beta inhibitor |
| CAS | 663619-89-4 |
| MW: | 364.4 D |
From 44.00€
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TGX-221
Item number: SYN-1089-M001
Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. TGX221 is a potent, cell permeable ATP-competitive inhibitor of PI3K, with selectivity for the p110beta isoform (IC(50) of 50nM). Target: PI3K , Kinase Group: Lipid Kinase , Substrate: Lipid
| Keywords: | TGX221 |
| Application: | PI3K p110 beta inhibitor |
| CAS | 663619-89-4 |
| MW: | 364,5 D |
From 100.00€
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TGX-221
Item number: LKT-T2792.1
p110beta PI3K inhibitor.
| Application: | PI3K p110beta inhibitor |
| CAS | 663619-89-4 |
| MW: | 364.44 D |
From 125.00€
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