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Glycine-beta-muricholic Acid
Glycine-beta-muricholic Acid

Item number: Cay9003230-10

Glycine-beta-muricholic acid (GbetaMCA) is an intestine-selective antagonist of the farnesoid X receptor (FXR) and the glycine-conjugated form of the murine-specific primary bile acid beta-muricholic acid (Cay-20287). It inhibits expression of the FXR target genes Shp and Fgf15 induced by the FXR ligands...
Keywords: Gly-MCA, GbetaMCA, N-[(3alpha,5beta,6beta,7beta)-3,6,7-trihydroxy-24-oxocholan-24-yl]-glycine
Application: FXR antagonist
CAS 66225-78-3
MW: 465.6 D
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