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Item number: TGM-T3445-100mg

Description: Importazole is an inhibitor of the nuclear transport receptor importin-beta. Target: Others, Apoptosis. Smiles: CC(Nc1nc(nc2ccccc12)N1CCCC1)c1ccccc1. References: Soderholm JF, et al. ACS Chem Biol. 2011, 6(7):700-8.

Application:	Cell-permeable importin-beta inhibitor
CAS	662163-81-7
MW:	318.42 D

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Importazole

Item number: Cay21491-5

Importazole is a cell-permeable inhibitor of importin-beta, which transports cargo molecules bearing a nuclear localization signal into the nucleus. Importazole prevents nuclear import of GFP-tagged nuclear factor of activated T cells (NFAT-GFP) in HEK293 cells (IC50 = 15 µM), which is reversible upon importazole...

Keywords:	IPZ, N-(1-phenylethyl)-2-(1-pyrrolidinyl)-4-quinazolinamine
Application:	Cell-permeable importin-beta inhibitor
CAS	662163-81-7
MW:	318.4 D

From 85.00€ *

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