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N-desmethyl Loperamide
Item number: Cay16126-1
Loperamide (Cay-14875) is an opiate which potently and selectively activates µ opioid receptors (Ki = 0.16 nM) exclusively in the periphery. N-desmethyl Loperamide is a major metabolite of loperamide. Like loperamide, N-desmethyl loperamide is a substrate of the ATP-dependent efflux transporter, P-glycoprotein. As a...
| Keywords: | R 20905, 4-(4-chlorophenyl)-4-hydroxy-N-methyl-alpha,alpha-diphenyl-1-piperidinebutanamide |
| Application: | Analytical reference standard, major loperamide metabolite |
| CAS | 66164-07-6 |
| MW: | 463 D |
From 246.00€
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N-Desmethyl Loperamide
Item number: TGM-T33615-1mg
Description: N-Desmethyl Loperamide is the major metabolite of loperamide. It is also used as the precusor for radiolabelled loperamide. Target: Others. Smiles: O=C(NC)C(C=1C=CC=CC1)(C=2C=CC=CC2)CCN3CCC(O)(C4=CC=C(Cl)C=C4)CC3. References: Vaz RJ, Kang J, Luo Y, Rampe D. Molecular determinants of loperamide and...
| Keywords: | R 20905, R-20905, dLop, R20905 |
| Application: | Major loperamide metabolite |
| CAS | 66164-07-6 |
| MW: | 463.01 D |
From 450.00€
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