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N-didesmethyl Loperamide
N-didesmethyl Loperamide

Item number: Cay39559-1

N-didesmethyl Loperamide is an active metabolite of the peripheral µ1-opioid receptor agonist loperamide. It inhibits electricity-induced contractions in isolated guinea pig myenteric plexus (IC50 = 370 nM). N-didesmethyl Loperamide sensitizes a chloroquine-resistant P. falciparum strain to chloroquine (EC50 = 482...
Keywords: R 21345, 4-(4-chlorophenyl)-4-hydroxy-alpha,alpha-diphenyl-1-piperidinebutanamide
Application: Active loperamide ametabolite
CAS 66164-06-5
MW: 449 D
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