3 products were found matching "65646-68-6"!
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Fenretinide
Item number: TGM-T1872-100mg
Description: Fenretinide (4-HPR) is an orally-active synthetic retinoid derivative with potential antineoplastic and chemopreventive activities. Target: Autophagy, Retinoid Receptor. Smiles: C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(=O)Nc1ccc(O)cc1. References: Apraiz, Aintzane., et al. Dihydroceramide...
| Keywords: | 4-hydroxy(phenyl)retinamide, MK-4016, 4-HPR |
| Application: | Antineoplastic |
| CAS | 65646-68-6 |
| MW: | 391.55 D |
From 34.00€
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Fenretinide
Item number: Cay17688-50
Fenretinide is a synthetic derivative of retinoic acid (Cay-11017) and an inhibitor of dihydroceramide desaturase (IC50 = 2.32 µM). It promotes the generation of reactive oxygen species (ROS), the degradation of anti-apoptotic MCL-1, and the cleavage of pro-apoptotic PKCdelta. At 5-20 µM, fenretinide selectively...
| Keywords: | 4-HPR, 4-Hydroxy(phenyl)retinamide, MK-4016, Retinoic Acid p-hydroxyphenylamide, Ro 22-4667, N-(4-hydroxyphenyl)-retinamide |
| Application: | Retinoic acid receptor gamma activator |
| CAS | 65646-68-6 |
| MW: | 391.6 D |
From 125.00€
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N-(4-Hydroxyphenyl)retinamide
Item number: LKT-H9613.1
A synthetic analog of vitamin A without the observed liver toxicity. Cancer chemopreventive agent. Induces apoptosis in human cancer cell lines.
| Application: | Apoptosis inducer |
| CAS | 65646-68-6 |
| MW: | 391,55 D |
From 94.00€
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