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MT-DADMe-ImmA
MT-DADMe-ImmA

Item number: TGM-TQ0008-100mg

Description: MT-DADMe-ImmA (MTDIA) is an inhibitor of human 5'-methylthioadenosine phosphorylase (MTAP, Ki: 90 pM). Target: Others. Smiles: CSC[C@H]1CN(Cc2c[nH]c3c(N)ncnc23)C[C@@H]1O. References: Evans GB, et al. Second generation transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase. J...
Keywords: Methylthio-DADMe-Immucillin A, MTDIA
Application: MTAP inhibitor
CAS 653592-04-2
MW: 293.39 D
From 63.00€ *
Review
MT-DADMe-ImmA
MT-DADMe-ImmA

Item number: Cay29711-1

MT-DADMe-ImmA is an inhibitor of 5'-methylthioadenosine phosphorylase (MTAP, Ki = 1.7 nM). It increases levels of MTA (Cay-15593), a product of polyamine metabolism, in FaDu human squamous cell carcinoma cells when used at a concentration of 1 µM. MT-DADMe-ImmA (5, 9, and 21 mg/kg per day for 28 days) reduces tumor...
Keywords: Methylthio-DADMe-Immucillin A, MTDIA,...
Application: MTAP inhibitor
CAS 653592-04-2
MW: 293.4 D
From 52.00€ *
Review