Description: Kemptide is a synthetic heptapeptide, acting as a substrate for cAMP-dependent protein kinase (PK). Target: PKA. Smiles: CC(C)CCC(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(C)C(=O)NC(CO)C=O. References: Kübler D, et al. Evidence for ecto-protein kinase activity that phosphorylates Kemptide in a cyclic...

Kemptide is a synthetic heptapeptide that acts as a specific substrate for cAMP-dependent protein kinase (PKA) as it carries the recognition and phosphorylation site of PKA. Various cultured cells can catalyze the phosphorylation of kemptide in the presence of extracellular ATP and cAMP (Kms = 3-4 µM) with plasma...

A synthetic heptapeptide substrate for kinases that maintains cell membrane intactness when added to cultured cells.