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Item number: Cay18460-250

Nicorandil is an activator of sulfonylurea receptor 2B (SUR2B) linked to ATP-sensitive potassium channel Kir6.2 (EC50 = ~10 µM) and a nitric oxide (NO) donor. It is selective for SUR2B/Kir6.2 over the SUR2A/Kir6.2 channel (EC50 = >500 µM). Nicorandil activates soluble guanylate cyclase in a cell-free assay and...

Keywords:	2-Nicotinamidoethyl nitrate, SG-75, N-[2-(nitrooxy)ethyl]-3-pyridinecarboxamide
Application:	ATP-sensitive potassium channel (SUR1/Kir6.2) opener, Nitric oxide donor
CAS	65141-46-0
MW:	211.2 D

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