- Search results for 639089-54-6
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4 products were found matching "639089-54-6"!
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Item number: SYN-1092-M001
Soluble in DMSO or ethanol. In mammals, three Aurora kinases, Aurora A, Aurora B, and Aurora C, are expressed. Aurora C expression is mainly restricted to testis, where it functions during meiosis, whereas Aurora A and B play key functions regulating mitosis. Aurora A is localized to the centrosome and spindle...
Keywords: | MK-0457, VX-680 |
Application: | Aurora inhibitor |
CAS | 639089-54-6 |
MW: | 464,6 D |
From 66.00€
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Item number: T8078.10
Tozasertib is a potent inhibitor of all aurora kinases, including the A, B and C isotypes (Ki=0.6nM, 18nM and 4.6nM, respectively). It also inhibits ABL kinase (Ki=30nM), an imatinib-resistant ABL mutant (T315I) kinase (Ki=42nM), and Flt-3 (Ki=30nM). Tozasertib binds to an inactive aurora conformation. Solubility:...
CAS | 639089-54-6 |
MW: | 464.59 |
107.00€
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Item number: Cay13600-100
The Aurora kinases (A, B, and C) are a family of serine-threonine kinases that regulate various stages of mitotic function. With significant roles in cell cycle and cell division, Aurora kinase gene amplification and overexpression are linked to tumorigenesis. MK-0457 is a potent pan-Aurora kinase inhibitor but...
Keywords: | Tozasertib, VX-680,... |
Application: | Aurora kinase inhibitor |
CAS | 639089-54-6 |
MW: | 464.6 D |
From 115.00€
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![Tozasertib Tozasertib](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
Item number: LKT-T5996.25
Tozasertib (VX680) is an Aurora kinase inhibitor found to suppress tumor growth.
Keywords: | VX680, MK0457, VX-680, MK-0457 |
Application: | Aurora kinase inhibitor |
CAS | 639089-54-6 |
MW: | 464,59 D |
From 79.00€
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