Description: Sulfanilamide (UK-124) can competitively inhibit bacterial enzyme dihydropteroate synthetase with IC50 of 320 µM. Target: Antibiotic, Autophagy, Antibacterial. Smiles: Nc1ccc(cc1)S(N)(=O)=O. References: McCullough JL, et al. Antimicrob Agents Chemother, 1973, 3(6), 665-669.

Sulfanilamide is a sulfonamide antibiotic. It is bacteriostatic against Streptococcus when used at a concentration of 20 µg/ml and inhibits the growth of 106 clinical isolates of Gonococcus at 0.01% v/v. Sulfanilamide reduces plasma levels of Streptococcus in infected rabbits. It is an inhibitor of carbonic...