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JNJ-10198409

Item number: TGM-T15616-100mg

Description: JNJ- 10198409 is a relatively selective and ATP competitive PDGF-RTK inhibitor (IC50=2 nM). JNJ-10198409 has good activity against PDGFR-beta kinase (IC50=4.2 nM) and PDGFR-alpha kinase (IC50=45 nM). It is a dual-mechanism, antiangiogenic, and tumor cell antiproliferative agent. Target: PDGFR. Smiles:...

Keywords:	JNJ-10198409
Application:	PDGF-BB inhibitor
CAS	627518-40-5
MW:	325.34 D

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JNJ-10198409

Item number: Cay10008131-1

Inhibition of the tyrosine kinase activity of growth factor receptors such as the platelet-derived growth factor (PDGF-BB) receptor can have potent antiangiogenic and antiproliferative activity. JNJ-10198409 is a small molecule inhibitor of platelet-derived growth factor (PDGF-BB) tyrosine kinase with an IC50 value...

Keywords:	N-(3-fluorophenyl)-1,4-dihydro-6,7-dimethoxy-indeno[1,2-c]pyrazol-3-amine
Application:	PDGF-BB inhibitor
CAS	627518-40-5
MW:	325.3 D

From 39.00€ *

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