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Nelociguat
Item number: TGM-T7201-100mg
Description: Nelociguat (BAY60-4552)(BAY60-4552) is a soluble guanylate cyclase stimulator (sGC stimulator). Soluble guanylate cyclase (sGC) is a key enzyme in the nitric oxide (NO) signalling pathway. Target: Guanylate cyclase. Smiles: COC(=O)Nc1c(N)nc(nc1N)-c1nn(Cc2ccccc2F)c2ncccc12. References: Oudot A ,...
| Keywords: | BAY60-4552 |
| Application: | Soluble guanylate cyclase and an active metabolite riociguat stimulator |
| CAS | 625115-52-8 |
| MW: | 408.39 D |
From 31.00€
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Nelociguat
Item number: Cay34133-10
Nelociguat is a stimulator of soluble guanylate cyclase (sGC) and an active metabolite of riociguat (Cay-9000554). It is formed from riociguat by the cytochrome P450 (CYP) isoform CYP1A1. Nelociguat increases phosphorylation of the protein kinase G (PKG) substrate vasodilator-stimulator protein (VASP) in isolated...
| Keywords: | BAY 60-4552, Desmethyl Riociguat,... |
| Application: | Soluble guanylate cyclase and an active metabolite riociguat stimulator |
| CAS | 625115-52-8 |
| MW: | 408.4 D |
From 117.00€
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