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Item number: Cay21803-5

MK-0812 is an antagonist of chemokine (C-C) motif receptor 2 (CCR2, IC50 = 5 nM for the human receptor). It inhibits mammosphere formation of BT-549 breast cancer cells, an effect that is enhanced by the beta-catenin inhibitor PNU 74654 (Cay-16349). MK-0812 (0.03, 0.1, and 0.3 mg/kg) increases chemokine (C-C) motif...

Keywords:	1,5-anhydro-2,3-dideoxy-3-[[(1R,3S)-...
Application:	CCR2 antagonist
CAS	624733-88-6
MW:	469.5 D

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