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Ki20227
Ki20227

Item number: TGM-T4315-100mg

Description: Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM). It also has certain inhibitory against VEGFR2(IC50: 12 nM) and c-Kit/PDGFRbeta(IC50: 451/217 nM), respectively. Target: c-Fms, CSF-1R, PDGFR, c-Kit, VEGFR. Smiles: COc1cc(Oc2ccnc3cc(OC)c(OC)cc23)ccc1NC(=O)NC(C)c1nccs1....
Application: CSF-1 receptor inhibitor
CAS 623142-96-1
MW: 480.54 D
From 40.00€ *
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Ki20227
Ki20227

Item number: Cay22258-1

Ki20227 is an inhibitor of macrophage colony stimulating factor 1 (CSF1) receptor tyrosine kinase (c-Fms, IC50 = 2 nM). It inhibits CSF1-dependent c-Fms phosphorylation in a dose-dependent manner in RAW264.7 cells and reduces CSF1-dependent growth of M-NFS-60 cells (IC50 = 14 nM). Ki20227 suppresses development of...
Keywords: N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]-2-methoxyphenyl]-N'-[1-(2-thiazolyl)ethyl]-urea
Application: CSF-1 receptor inhibitor
CAS 623142-96-1
MW: 480.5 D
From 45.00€ *
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Ki-20227
Ki-20227

Item number: SYN-1049-M001

Soluble in DMSO or ethanol. Ki20227 is a c-fms tyrosine kinase inhibitor. It has IC(50) values of 2, 12, 451 and 217nM for c-Fms, VEGFR-2, c-Kit and PDGFRbeta respectively. Target: c-fms , Kinase Group: RTK , Substrate: Tyrosine
Keywords: Ki-20227
Application: c-fms inhibitor
CAS 623142-96-1
MW: 480,5 D
From 154.00€ *
Review