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Carmofur
Item number: TGM-T1307-100mg
Description: Carmofur (HCFU) is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer. Carmofur has been known to induce leukoencephalopathy. Target: DNA/RNA Synthesis, SARS-CoV, Nucleoside Antimetabolite/Analog, Virus Protease. Smiles: CCCCCCNC(=O)n1cc(F)c(=O)[nH]c1=O....
| Keywords: | HCFU |
| Application: | Targets thymidylate synthase [EC:2.1.1.45] (thyA, TYMS) |
| CAS | 61422-45-5 |
| MW: | 257.26 D |
From 31.00€
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Carmofur
Item number: Cay14243-1
Carmofur is an inhibitor of acid ceramidase (IC50 = 79 nM for the rat enzyme) and a derivative of 5-flurouracil (Cay-14416). It reduces acid ceramidase activity in a dose- and time-dependent manner and induces intracellular accumulation of various ceramide species, including C18 ceramide (Cay-19556), C16 ceramide...
| Keywords: | HCFU, 5-fluoro-N-hexyl-3,4-dihydro-2H,4-dioxo-1-pyrimidinecarboxamide |
| Application: | Acid ceramidase inhibitor |
| CAS | 61422-45-5 |
| MW: | 257.3 D |
From 49.00€
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Carmofur
Item number: LKT-C0174.1
Pyrimidine analog, fluorouracil derivative, thymidylate synthase inhibitor.
| Keywords: | HCFU, Mifurol, Yamaful, 5-Fluoro-N-hexyl-3,4-dihydro-2,4-1(2H)- pyrimidinecarboxamide |
| Application: | Metabolic studies |
| CAS | 61422-45-5 |
| MW: | 257,26 D |
186.00€
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