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Item number: TGM-T1741-100mg

Description: AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor. Target: GSK-3. Smiles: Oc1[nH]c2ccc(cc2c1-c1ccc(CN2CCOCC2)cn1)C#N. References: Georgievska B, et al. J Neurochem, 2013, 125(3), 446-456.

Application:	Brain permeable GSK3alpha/beta inhibitor
CAS	612487-72-6
MW:	334.37 D

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AZD 1080

Item number: Cay16676-1

The two isoforms of glycogen synthase kinase 3, GSK3alpha and GSK3beta, constitutively phosphorylate and inactivate glycogen synthase, preventing glycogen synthesis. They also phosphorylate proteins that are relevant to Alzheimer's disease and osteogenesis. AZD 1080 is a potent, brain permeable inhibitor of...

Keywords:	2-hydroxy-3-[5-(4-morpholinylmethyl)-2-pyridinyl]-1H-indole-5-carbonitrile
Application:	Brain permeable GSK3alpha/beta inhibitor
CAS	612487-72-6
MW:	334.4 D

From 39.00€ *

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