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Item number: Cay21849-1

P1075 is a potent activator of sulfonylurea receptor 2-associated ATP-sensitive potassium channels (SUR2-Kir6) with an EC50 value of 45 nM for SUR2B-Kir6 channel activation. It is highly selective for SUR2 over SUR1 isoforms (IC50s = 9-46 nM and 1.02 mM, respectively, in a radioligand binding assay). P1075 increases...

Keywords:	N-cyano-N'-(1,1-dimethylpropyl)-N''-3-pyridinyl-guanidine
Application:	Kir6 channel opener
CAS	60559-98-0
MW:	231.3 D

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