Description: Dansyl chloride (DNSC-l) reacts with primary amino groups in both aliphatic and aromatic amines to produce stable blue- or blue-green-fluorescent sulfonamide adducts. It is widely used to modify amino acids, specifically, protein sequencing and amino acid analysis. Target: Others. Smiles:...

Dansyl chloride is a reactive probe for the derivatization of primary amines, including those on amino acids, peptides, and polyamines, for detection by HPLC. It has also been used for the derivatization of compounds containing phenol groups, such as steroids, for detection by MS/MS. Dansyl chloride is a fluorescent...

Dansyl chloride is non-fluorescent until it reacts with amines. It is particularly useful for preparing fluorescent drug or ligand analogs that are expected to bind to hydrophobic sites in proteins or membranes or other biological receptors.

Yellow to orange powder. Soluble in DMF, acetone, chloroform, pyridine, benzene or dioxane. Insoluble in water. Unstable in DMSO solutions. Chemical. CAS: 605-65-2. Formula: C12H12ClNO2S. MW: 269.75. Synthetic. Dansyl chloride is a fluorogenic probe that reacts with primary amino groups in both aliphatic and...