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Pifithrin-alpha, p-Nitro, Cyclic
Pifithrin-alpha, p-Nitro, Cyclic

Item number: TGM-T12472-100mg

Description: Pifithrin-alpha, p-Nitro, Cyclic (PFN-alpha) is a cell-permeable, active-form inhibitor of p53. Target: p53. Smiles: [O-][N+](=O)C1=CC=C(C=C1)C1=CN2C(SC3=C2CCCC3)=N1. References: Pietrancosta N, et al. Imino-tetrahydro-benzothiazole derivatives as p53 inhibitors: discovery of a highly potent in vivo...
Keywords: PFN-alpha
Application: Cell-permeable p53 inhibitor
CAS 60477-38-5
MW: 299.35 D
From 34.00€ *
Review
p-nitro-Cyclic Pifithrin-alpha
p-nitro-Cyclic Pifithrin-alpha

Item number: Cay17848-1

Pifithrin-alpha (PFT-alpha, Cay-13326) is an inactivator of p53 that blocks p53-dependent transcriptional activation and apoptosis. Cyclic PFT-alpha (Cay-14748) is a stable analog of PFT-alpha. p-nitro-Cyclic PFT-alpha is a cell-permeable form of cyclic PFT-alpha. It is one order of magnitude more active that...
Keywords: p-nitro-Cyclic PFT-alpha, Cyclic pifithrin-alpha-p-nitro, 5,6,7,8-tetrahydro-2-(4-nitrophenyl)-imidazo[2,1-b]benzothiazole
Application: Cell-permeable p53 inhibitor
CAS 60477-38-5
MW: 299.3 D
From 50.00€ *
Review