Description: Bufuralol hydrochloride (Ro 3-4787 hydrochloride) is a potent non-selective, orally active beta-adrenoreceptor antagonist with partial agonist activity, which is also a CYP2D6 probe substrate [1] [2]. Target: Others. Smiles: Cl.OC(C=1OC2=C(C=CC=C2CC)C1)CNC(C)(C)C

Bufuralol is a non-selective antagonist of beta-adrenergic receptors (beta-ARs) that also has partial agonist activity. It decreases mean arterial blood pressure and increases abdominal aortic blood flow in anesthetized cats when administered intravenously at doses of 0.3 and 1 mg/kg. Bufuralol is hydroxylated at...