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Item number: TGM-T4565-100mg

Description: Tafamidis (Fx-1006A) is a kinetic stabilizer of transthyretin (TTR) that prevents amyloidogenesis by wild-type and mutant TTRs. It binds to TTR with negative cooperativity (Kd1: 3 nM, Kd2: 278 nM) to stabilize the TTR dimer-dimer interface and inhibit tetrameric dissociation. Tafamidis stabilizes...

Keywords:	Fx-1006A
Application:	Targets transthyretin (TTR)
CAS	594839-88-0
MW:	308.12 D

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Tafamidis

Item number: Cay13694-5

Tafamidis is a kinetic stabilizer of transthyretin (TTR) that prevents amyloidogenesis by wild-type and mutant TTRs. It binds to TTR with negative cooperativity (Kd1 = 3 nM, Kd2 = 278 nM) to stabilize the TTR dimer-dimer interface and inhibit tetrameric dissociation. Tafamidis stabilizes wild-type and clinically...

Keywords:	PF-06291826, 2-(3,5-dichlorophenyl)-6-benzoxazolecarboxylic acid
Application:	TTR kinetic stabilizer, amyloidogenesis suppressant
CAS	594839-88-0
MW:	308.1 D

From 92.00€ *

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