Description: 1. Cucurbitacin IIA (Dihydrocucurbitacin Q1) can induce apoptosis and enhance autophagy , contributes to the anti-inflammatory activity of Cucurbitacin IIA against inflammation-related diseases. 2. Cucurbitacin IIA is a novel class of anti-cancer drug in suppression of cancer cell expansion by...

Cucurbitacin IIa is a triterpenoid that has been found in H. amabilis and has diverse biological activities. It decreases the proliferation of (IC50 = 370 nM), and induces cell cycle arrest at the G2/M phase and apoptosis in, HT-29 colorectal adenocarcinoma cells when used at a concentration of 1 µM. Cucurbitacin...