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Item number: TGM-T6545-100mg

Description: IOX1 is the most effective broad-spectrum 2OG oxygenases(including the JmjC demethylases) inhibitor. The IC50 of IOX1 for KDM4A, KDM3A, is 0.6 and 0.1 uM, respectively. Target: Histone Demethylase. Smiles: OC(=O)c1ccc(O)c2ncccc12. References: Schiller R, et al. ChemMedChem. 2014, 9(3), 566-571.

Application:	JMJD demethylase inhibitor
CAS	5852-78-8
MW:	189.17 D

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IOX1

Item number: Cay11572-10

2-oxoglutarate (2OG) and other Fe(II)-dependent oxygenases are an important family of enzymes with roles in collagen biosynthesis, lipid metabolism, nucleic acid repair and modification, histone demethylation, and hypoxic sensing. Impaired 2OG oxygenase activity is linked to the cellular hypoxic response and various...

Keywords:	8-hydroxy-5-quinolinecarboxylic acid
Application:	2OG oxygenase inhibitor
CAS	5852-78-8
MW:	189.2 D

From 117.00€ *

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