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SU4312
Item number: TGM-T3570-10mg
Description: SU-4312, also known as DMBI, is a potent and selective inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 values are 0.8 and 19.4 µM respectively). SU4312 (SU 4312) unexpectedly protects against MPP(+) -induced neurotoxicity via selective and direct inhibition of neuronal NOS. Target: PDGFR, VEGFR....
| Keywords: | SU 4312, NSC 86429 |
| Application: | Selective, cell-permeable VEGFR2 / PDGFR inhibitor |
| CAS | 5812-07-7 |
| MW: | 264.32 D |
From 34.00€
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SU 4312
Item number: Cay20213-1
SU 4312 is a selective, cell-permeable inhibitor of VEGFR2 and PDGFR tyrosine kinases (IC50s = 0.8 and 19.4 µM, respectively). It demonstrates IC50 values >100 µM at EGFR, HER2, and IGF-1R. SU 4312 has been shown to inhibit VEGF-dependent angiogenesis in a zebrafish assay (IC50 = 1.8 µM) without affecting normal...
| Keywords: | NSC 86429, 3-[[4-(dimethylamino)phenyl]methylene]-1,3-dihydro-2H-indol-2-one |
| Application: | Selective, cell-permeable VEGFR2 / PDGFR inhibitor |
| CAS | 5812-07-7 |
| MW: | 264.3 D |
From 43.00€
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