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Item number: TGM-T13276-100mg

Description: VAF347 is a cell-permeable and highly affinity agonist of the aryl hydrocarbon receptor (AhR) with anti-inflammatory effects. Target: Aryl Hydrocarbon Receptor. Smiles: FC(F)(F)c1ccc(Nc2nccc(n2)-c2cccc(Cl)c2)cc1. References: Ibabao CN, et al. The AhR agonist VAF347 augments retinoic acid-induced...

Application:	AhR agonist
CAS	574759-62-9
MW:	349.74 D

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VAF347

Item number: Cay37328-1

VAF347 is an agonist of the aryl hydrocarbon receptor (AhR). It binds to AhR in a radioligand binding assay using guinea pig hepatic cytosol and induces mRNA expression of the AhR target gene CYP1A1 in isolated human peripheral blood mononuclear cells (PBMCs) when used at a concentration of 50 nM. VAF347 (20 µM)...

Keywords:	4-(3-chlorophenyl)-N-[4-(trifluoromethyl)phenyl]-2-pyrimidinamine
Application:	AhR agonist
CAS	574759-62-9
MW:	349.7 D

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