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Item number: TGM-T14040-10mg

Description: 4-Hydroxytolbutamide(Hydroxytolbutamide), a metabolite of Tolbutamide, which is metabolized by CYP2C8 and CYP2C9. Tolbutamide is a first generation potassium channel blocker and a sulfonylurea oral antidiabetic[1][2]. Target: Potassium Channel. Smiles: CCCCNC(=O)NS(=O)(=O)c1ccc(CO)cc1. References:...

Keywords:	Hydroxytolbutamide
CAS	5719-85-7
MW:	286.35 D

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4-hydroxy Tolbutamide

Item number: Cay10008520-1

4-hydroxy Tolbutamide is a metabolite of the potassium channel antagonist tolbutamide (Cay-19888). It is formed from tolbutamide by the cytochrome P450 (CYP) isoform CYP2C9 in human liver microsomes and COS-7 cell lysates expressing the human enzyme. 4-hydroxy Tolbutamide has been used as a marker of CYP2C9 activity...

Keywords:	N-[(butylamino)carbonyl]-4-(hydroxymethyl)-benzenesulfonamide
Application:	Bioactive lipid assays
CAS	5719-85-7
MW:	286.4 D

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