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Item number: Cay17754-5

Erastin, named for eradicator of RAS and small T (ST) antigen-expressing cells, is a ferroptosis inducer. It induces ferroptotic cell death in vitro, an effect that can be blocked by the ferroptosis inhibitors ciclopirox olamine, Trolox (Cay-10011659), ferrostatin-1 (Cay-17729), U-0126 (Cay-70970), cycloheximide...

Keywords:	2-[1-[4-[2-(4-chlorophenoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-quinazolinone
Application:	Antitumor agent
CAS	571203-78-6
MW:	547.1 D

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Erastin

Item number: TGM-T1765-1mg

Description: Erastin is an ferroptosis activator that acts on the mitochondrial VDAC in a ROS- and iron-dependent manner. Erastin has anti-tumor activity and acts selectively on tumor cells with RAS-carcinogenic mutations. The product is unstable in solution and is recommended to be dispensed now. Target: VDAC,...

Application:	Antitumor agent
CAS	571203-78-6
MW:	547.04 D

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