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Mavorixafor
Item number: TGM-TQ0174-100mg
Description: Mavorixafor (AMD-070) is an effective and selective antagonist of CXCR4, with an IC50 value of 13 nM against CXCR4 125I-SDF binding. Mavorixafor inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells (IC50 = 1 nM) and PBMCs (IC50 = 9 nM). Target: CXCR. Smiles:...
| Keywords: | AMD-070 |
| Application: | Targets C-X-C chemokine receptor type 4 (CXCR4, CD184) |
| CAS | 558447-26-0 |
| MW: | 349.47 D |
From 63.00€
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Mavorixafor
Item number: Cay28439-10
Mavorixafor is a chemokine (C-X-C motif) receptor 4 (CXCR4) antagonist (IC50 = 13 nM in a radioligand binding assay). It is selective for CXCR4 over chemokine (C-C motif) receptor 1 (CCR1), CCR2b, CCR4, CCR5, CXCR1, and CXCR2 (IC50s = >10 µM for all). Mavorixafor reduces chemotaxis of CCRF-CEM T cells induced by...
| Keywords: | AMD 070, AMD 11070, X4P-001, N1-(1H-benzimidazol-2-ylmethyl)-N1-[(8S)-5,6,7,8-tetrahydro-8-quinolinyl]-1,4-butanediamine |
| Application: | CXCR4 antagonist |
| CAS | 558447-26-0 |
| MW: | 349.5 D |
From 158.00€
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