Description: Phytosphingosine is a phospholipid with anticancer properties. In cancer cells, Phytosphingosine induces cell apoptosis through activation of caspase 8 and translocation of Bax. Target: Apoptosis. Smiles: CCCCCCCCCC CCCC[C@@H](O)[C@@H](O)[C@@H](N)CO. References: Moon-Taek Park, et al. Phytosphingosine...

Phytosphingosine is a sphingolipid with a hydroxyl group at the C4 position that is found mainly in fungi and plants but also in animals, including humans. It is metabolized to odd-numbered fatty acids with 2-hydroxy palmitic acid (Cay-22679) as an intermediate. Phytosphingosine dose-dependently induces cell death...