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McNA343
McNA343

Item number: Cay30961-10

McNA343 is a partial agonist of muscarinic acetylcholine receptors (Kis = 5, 1, 5, 0.2, and 7.6 µM for M1-5 receptors, respectively, in radioligand binding assays). It induces contraction of isolated human umbilical veins (EC50 = 1.23 µM), an effect that can be reversed by various M1 muscarinic receptor selective...
Keywords: 4-[[[(3-chlorophenyl)amino]carbonyl]oxy]-N,N,N-trimethyl-2-butyn-1-aminium, monochloride
Application: Muscarinic acetylcholine receptor partial agonist
CAS 55-45-8
MW: 317.2 D
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McN-A 343
McN-A 343

Item number: TGM-T22963-100mg

Description: McN-A 343 is a selective M1 muscarinic agonist known for its ability to stimulate muscarinic transmission in sympathetic ganglia. It has been found to effectively reduce inflammation and oxidative stress in experimental models of ulcerative colitis. Target: AChR. Smiles:...
CAS 55-45-8
MW: 317.21 D
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