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Apilimod
Apilimod

Item number: TGM-T2018-100mg

Description: Apilimod (STA 5326) inhibits the production of IL-12 and IL-23 and reduces dendritic cell infiltration in psoriasis. Target: PI3K, Interleukin, IL Receptor. Smiles: Cc1cccc(\C=N\Nc2cc(nc(OCCc3ccccn3)n2)N2CCOCC2)c1. References: Wada Y, et al. PLoS One. 2012,7(4):e35069.
Keywords: STA 5326
CAS 541550-19-0
MW: 418.49 D
From 43.00€ *
Review
Apilimod
Apilimod

Item number: Cay19094-5

Apilimod is an inhibitor of the class III phosphatidylinositol kinase PIKfyve (IC50 = 14 nM). It is selective for PIKfyve over 10 other lipid kinases and 31 other protein kinases (IC50s = >9.1 µM for all). Apilimod inhibits the production of IL-12p40 induced by IFN-gamma and LPS or the TLR7 agonist R-837 (imiquimod,...
Keywords: STA-5326, 3-methyl-2-[6-(4-morpholinyl)-2-[2-(2-pyridinyl)ethoxy]-4-pyrimidinyl]hydrazone, benzaldehyde
Application: PIKfyve inhibitor, IL-12p40 production inhibitor
CAS 541550-19-0
MW: 418.5 D
From 55.00€ *
Review