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Item number: TGM-T12608-100mg

Description: QX-314 chloride is a membrane-impermeable, permanently charged blocker of the sodium channel. Target: Sodium Channel. Smiles: [Cl-].CC[N+](CC)(CC)CC(=O)Nc1c(C)cccc1C. References: Rivera-Acevedo RE, et al. The quaternary lidocaine derivative, QX-314, exerts biphasic effects on transient receptor...

Application:	Sodium channel blocker
CAS	5369-03-9
MW:	298.85 D

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QX-314 (chloride)

Item number: Cay18454-50

QX-314 is a membrane-impermeant lidocaine derivative that selectively blocks sodium channels on nociceptive neurons when delivered intracellularly via the TRPV1 channel, but is reportedly ineffective with extracellular application. When supplied in combination with 1 µM capsaicin (Cay-92350), a TRPV1 receptor...

Keywords:	N-Ethyllidocaine, 2-[(2,6-dimethylphenyl)amino]-N,N,N-triethyl-2-oxo-ethanaminium, monochloride
Application:	Sodium channel blocker
CAS	5369-03-9
MW:	298.9 D

163.00€ *

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