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TMB 8 (hydrochloride)
TMB 8 (hydrochloride)

Item number: Cay23928-10

TMB 8 is a non-competitive antagonist of nicotinic acetylcholine receptors (nAChRs) with IC50 values of 390 and 350 nM, respectively, for human muscle-type and alpha3beta4 subunit-containing ganglionic nAChRs expressed in TE671/RD or SH-SY5Y cells. It inhibits nicotine-induced dopamine release from rat brain...
Keywords: 3,4,5-trimethoxy-benzoic acid, 8-(diethylamino)octyl ester, monohydrochloride
Application: Nicotinic acetylcholine receptor non-competitive antagonist
CAS 53464-72-5
MW: 432 D
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