Description: Tropolone, a metal chelator, possesses weak antioxidative and radical-scavenging properties and shows a strong affinity for ferric ion. Target: Tyrosinase. Smiles: O=C1C(O)=CC=CC=C1. References: Kahn V , Andrawis A . Inhibition of mushroom tyrosinase by tropolone[J]. Phytochemistry, 1985, 24(5):905-908.

Tropolone is a terpene that has been found in cupressaceous tree bark and has diverse biological activities. It inhibits catechol O-methyltransferase (COMT, Ki = 22 µM). Tropolone is bacteriostatic against a panel of Gram-positive and Gram-negative bacteria (MICs = 12-82 µM) and bactericidal against A. hydrophilia...