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Item number: TGM-T16506-100mg

Description: PF-4878691 (3M-852A) is a potent and selective Toll-like receptor 7 agonist, designed to dissociate its antiviral and inflammatory activities. Target: TLR. Smiles: CCc1nc2c(N)nc3ccccc3c2n1CCCCNS(C)(=O)=O. References: Fidock MD, et al. The innate immune response, clinical outcomes, and ex vivo HCV...

Keywords:	3M-852A
Application:	TLR7 agonist
CAS	532959-63-0
MW:	361.46 D

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852A

Item number: Cay39512-1

852A is a toll-like receptor 7 (TLR7) agonist. It selectively induces NF-kappaB signaling in HEK293 cells expressing recombinant human TLR7 but not HEK293 cells expressing recombinant human TLR8 or TLR9 when used at a concentration of 1 µM. 852A (10-1,000 ng/ml) also induces IFN-alpha production in plasmacytoid...

Keywords:	PF-4878691, N-[4-(4-amino-2-ethyl-1H-imidazo[4,5-c]quinolin-1-yl)butyl]-methanesulfonamide
Application:	TLR7 agonist
CAS	532959-63-0
MW:	361.5 D

From 54.00€ *

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