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Rapamycin
Rapamycin

Item number: Cay13346-1

Rapamycin is an allosteric inhibitor of the mammalian target of rapamycin (mTOR) complex 1 (mTORC1) originally isolated from S. hygroscopicus. It interacts with FKBP prolyl isomerase 1A (FKBP12) to form a complex that binds to and inhibits the kinase activity of mTORC1. Rapamycin inhibits growth of Rh1 and Rh30...
Keywords: AY 22989, NSC 226080, Wy 090217,...
Application: mTORC1 blocking
CAS 53123-88-9
MW: 914.2 D
From 50.00€ *
Review
Rapamycin
Rapamycin

Item number: AG-CN2-0025-M001

Isolated from Streptomyces hygroscopicus. Antibiotic. Antibacterial and antifungal properties. Forms a complex with FKBP12 and inhibits the molecular target of rapamycin (mTOR). Inhibits the response to interleukin-2 (IL-2), and thereby blocks activation of T and B cells. Potent immunosuppressant used as an...
Keywords: Sirolimus, Rapamune, NSC 226080, Antibiotic AY-22989, WY-090217, RAPA, SILA 9268A, CCRIS 9024
Application: mTOR inhibitor, Immunsuppressant, Apoptosis inducer
CAS 53123-88-9
MW: 914,2 D
From 28.00€ *
Review
Rapamycin
Rapamycin

Item number: LKT-R0161.10

Macrolide originally produced by Streptomyces, mTOR inhibitor.
Keywords: Sirolimus, Rapamune, AY-22989
Application: Antibiotic
CAS 53123-88-9
MW: 914,17 D
From 64.00€ *
Review
Rapamycin (FRAP, mTOR Inhibitor)
Rapamycin (FRAP, mTOR Inhibitor)

Item number: R1137-01.10

Rapamycin is a bacterial macrolide with antifungal and immunosuppressant activities , (1). Rapamycin forms a complex with the immunophilin FKBP12 which then inhibits the activity of FRAP/mTOR (TOR in yeast) (2,3). Rapamycin treatment of cells leads to the dephosphorylation and inactivation of p70 S6 kinase....
CAS 53123-88-9
MW: 914.20 D
From 265.00€ *
Review