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Sulfaphenazole
Item number: TGM-T4567-100mg
Description: Sulfaphenazole (Plisulfan) is an inhibitor of CYP2C9 (Ki: 0.3 µM) that demonstrates at least 100-fold selectivity over other CYP450 isoforms (Ki: 63/29 µM for CYP2C8/CYP2C18, respectively, and no activity at CYP1A1, CYP1A2, CYP3A4, CYP2C19). At 10 µM, sulfaphenazole has been shown to inhibit...
| Keywords: | Raziosulfa, Depocid, Depotsulfonamide, Plisulfan |
| Application: | Targets dihydropteroate synthase [EC:2.5.1.15] (folP) |
| CAS | 526-08-9 |
| MW: | 314.36 D |
From 48.00€
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Sulfaphenazole
Item number: Cay14844-250
CYP2C9 is a major cytochrome P450 enzyme that is involved in the metabolic clearance of various therapeutic agents. Disruption of this enzyme's activity can lead to adverse drug reactions. Sulfaphenazole is an inhibitor of CYP2C9 (Ki = 0.3 µM) that demonstrates at least 100-fold selectivity over other CYP450...
| Keywords: | Depocid, Depotsulfonamide, Plisulfan, Raziosulfa, 4-amino-N-(1-phenyl-1H-pyrazol-5-yl)-benzenesulfonamide |
| Application: | CYP2C9 inhibitor |
| CAS | 526-08-9 |
| MW: | 314.4 D |
From 161.00€
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